Job title: Upstream Development Engineer
Company: Eurofins
Job description: Company DescriptionEurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. It also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products.In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.In 2021, Eurofins generated total revenues of EUR 6.72 billion, and has been among the best performing stocks in Europe over the past 20 years.Job DescriptionThe Upstream development engineer will work in the upstream process development team to design, execute, and optimize consistent fed-batch cell culture processes to produce quality recombinant proteins through laboratory studies. As part of the team, they will ensure that these processes are predictable, scalable, and controlled using multiple sizes of bioreactors (ambr15, ambr250, and bench-top scale bioreactors). The position will support tech transfer of developed and locked cell culture processes to the pilot team and CMOs.Roles and Responsibilities:
- Conduct upstream process unit operations, which include cell banking, cell expansion, bioreactor process, optimization, and characterization.
- Work collaboratively within the department as well as cross-functional peers to execute various upstream studies using shake flasks, wave bioreactors, and benchtop bioreactors.
- Use high throughput tools such as AMBR15, AMBR25,0, and Robocolumns as well as analytical tools like cell counters, bioanalyzers to support studies.
- Coordinate with the testing team to submit a large number of study samples, compiling results received, analyzing data using data analysis tools such as Microsoft Excel, JMP, Spotfire etc., as well as summarizing the findings.
- Document experiments using an electronic lab notebook, in addition to supporting technical reports for studies.
QualificationsMinimum Qualifications:
- Bachelor’s degree in chemistry, biology, pharmacy, or related pharmaceutical science; 2-4 years relevant industry experience OR
- Bachelor’s degree in engineering or related discipline; 0-2 years relevant industry experience OR
- Master’s degree in chemistry, biology, pharmacy, engineering, or related pharmaceutical science; 0-2 years relevant industry experience
- Previous experience working in a biologics laboratory or a GMP manufacturing environment
- Experience with mammalian cell culture and aseptic techniques
- experience with bench-scale bioreactor operation and other instrumentation that supports cell culture, such:
- Metabolite Analyzers
- Shake Flasks
- Cell Culture Plates.
- Authorization to work in the United States indefinitely without restriction or sponsorship
The Ideal Candidate will Have:
- Experience with harvest filtration and chromatographic separations
- Experience optimizing upstream processes or expression conditions
- Familiarity with additional analytical tools or advanced bioreactor systems
- Experience troubleshooting critical issues or problems and resolving routine issues
- Strong communication skills, both verbal and written
- Strength in organization, attention to detail and self-motivation
Additional InformationThis position is Full-Time, Monday-Friday, 8:00 a.m. – 5:00 p.m. with overtime as needed and the potential for some off-shift hours as depending on the project. Candidates living within a commutable distance of Lexington, MA, are encouraged to apply.Excellent full-time benefits include:
- comprehensive medical coverage, dental, and vision options
- Life and disability insurance
- 401(k) with company match
- Paid vacation and holidays
Eurofins Lancaster Laboratories Professional Scientific Services® (PSS) is a global, award-winning insourcing solution that places our people at our clients’ sites, dedicated to running and managing laboratory services while eliminating headcount, co-employment, and project-management worries.We infuse our 55-year track record of scientific and laboratory operations expertise, as well as HR and great place to work best practices, to recruit, hire, train, and manage highly qualified scientists to perform laboratory services using our clients’ quality systems and equipment.To learn more about Eurofins Lancaster Laboratories, please explore our website .Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.
Expected salary:
Location: Lexington, MA
Job date: Sat, 24 May 2025 22:56:14 GMT
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