Job title: Scientist II, Biologics Drug Product Development
Company: AbbVie
Job description: Company DescriptionAbbVie’s mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at . Follow @abbvie on , , , , and .Job DescriptionThe Biologics Drug Product Development group within AbbVie is a global organization responsible for developing and characterizing drug product formulations and manufacturing processes for biologic therapeutics (antibodies, antibody-drug conjugates (ADCs), neurotoxins, and novel biologic formats) from preclinical development through clinical proof of concept.We have an exciting opportunity for a Scientist II to join our team at our Bay Area site in South San Francisco, CA. This position requires an onsite presence and involves lab-based functions. Successful candidates will thrive in a collaborative lab environment and engage in daily cross-functional interactions with fellow scientists.KEY RESPONSIBILITIES INCLUDE:
- As a technical expert in drug product, develop, optimize, and innovate biologic formulations to enable clinical studies in a phase appropriate manner.
- Conduct routine analytical characterization of stability samples to understand degradation pathways.
- Design and execute experiments independently for formulation development, drug product process development, and in-use studies to ensure stability and accurate administration.
- Analyze and interpret experimental data independently to address scientific inquiries aligned with project and management goals.
- Develop and refine formulations, methods, and protocols to drive innovation while ensuring reliability and scalability.
- Collaborate cross-functionally to achieve project timelines and objectives, applying a deep understanding of CMC and drug product development.
- Manage experimental timelines effectively and adjust plans as required in consultation with project leads and stakeholders.
- Stay well-informed with scientific literature to enhance technical expertise and apply it to assignments in drug product development.
- Generate and document high-quality scientific data using electronic lab notebooks.
- Present scientific plans and data effectively and document studies through comprehensive reports.
- Contribute to the conceptualization and writing of publications, presentations, and patents.
Qualifications
- Bachelor’s degree in Chemistry, Biochemistry, Chemical Engineering, Bioengineering, Pharmaceutical Sciences, or related field with at least 7 years of industry experience, or a Master’s degree with at least 5 years of industry experience.
- Individuals with a PhD need not apply.
- Proven experience in biologic formulation development for both liquid and lyophilized products. Experience in platform formulation development is a plus.
- Proficiency in biologic drug product process development, with hands-on experience with fillers, liquid handlers, and lyophilizers.
- Expertise in analytical techniques for protein characterization and stability testing (e.g., SEC, CE-SDS, icIEF, HIAC, MFI, DLS).
- Strong experience in computational/programming skills for automation of workflows and data processing (Hamilton liquid handlers or other automation instruments) is preferred.
- Experience in analytical method development is preferred.
- Strong attention to detail, organizational skills, and problem-solving capabilities.
- Excellent communication skills, both oral and written, with a commitment to maintaining detailed lab records.
- Eagerness to learn and apply new scientific techniques.
- Ability to manage multiple tasks efficiently within established timelines, with strong planning and analytical skills.
- Strong collaborative skills for working effectively within and outside the team.
Additional InformationApplicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
- This is an on-site opportunity located in AbbVie’s Bay Area site in South San Francisco, CA.
- The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
- We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
- This job is eligible to participate in our short-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company’s sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.US & Puerto Rico only – to learn more, visitUS & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
Expected salary:
Location: San Francisco, CA
Job date: Sat, 15 Feb 2025 23:24:19 GMT
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